Three stories about the world of opioids collide: a drug trafficker arranges a multi-cartel Fentanyl smuggling operation between Canada and the U.S., an architect recovering from an OxyContin addiction tracks down the truth behind her son's involvement with narcotics, and a university professor battles unexpected revelations about his research employer, a drug company with deep government influence bringing a new "non-addictive" painkiller to market.
Convicted felon Jimmy gets early parole after serving twelve years for armed robbery. Upon his release, he vows to give Annie, his childhood love, now dying from cancer, the best last year of her life - unfortunately it's not that simple.